منابع مشابه
Anti-Allergic Drugs Tranilast and Ketotifen Dose-Dependently Exert Mast Cell-Stabilizing Properties.
BACKGROUND Anti-allergic drugs, such as tranilast and ketotifen, inhibit the release of chemokines from mast cells. However, we know little about their direct effects on the exocytotic process of mast cells. Since exocytosis in mast cells can be monitored electrophysiologically by changes in the whole-cell membrane capacitance (Cm), the absence of such changes by these drugs indicates their mas...
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flavonoids polyphenolic compounds that exert many anti-inflammatory and anti-microbial effects, and exhibit an anti-allergic action. quercetin is a flavonoids that recently has raised many issues and shown evidence about its action as a potential drug to allergy. a chinese herbal formula, known as food allergy herbal formula (fahf) has been related with blocking of anaphylaxis to peanuts...
متن کاملThe effect of ketotifen on inflammatory markers in allergic conjunctivitis: an open, uncontrolled study
BACKGROUND The efficacy and safety of ketotifen eye drop treatment in allergic conjunctivitis (AC) management is perfectly known by several studies, but the mechanism of action at the biochemical levels is poorly understood so we decided to perform an open, uncontrolled study in order to investigate the effect of the topical administration of ketotifen fumarate 0.05% on biochemical markers of i...
متن کاملKetotifen in the management of chronic urticaria: resurrection of an old drug.
Ketotifen is an oral antiallergic drug developed in 1970 by Sandoz Pharmaceuticals of Switzerland. It is a benzocycloheptathiophene derivative and was initially marketed as an inhibitor of anaphylaxis.1 The pharmacodynamic properties of ketotifen are many, because it is an inhibitor of the release and/or activity of mast cell and basophil mediators, including histamine, neutrophil, and eosinoph...
متن کاملOxygen: an anti-inflammatory drug.
• Vol 9 • December 2007 874 Impaired tissue oxygenation and cellular hypoxia are major components in the pathophysiology of a large variety of clinical conditions, including acute and chronic ischemia, wounds and tissue trauma, infections, physical and chemical injuries, as well as inflammatory joint and connective tissue diseases [1]. Tissue hypoxia triggers an inflammatory response. Mechanism...
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ژورنال
عنوان ژورنال: Respiration
سال: 1980
ISSN: 0025-7931,1423-0356
DOI: 10.1159/000195024